منابع مشابه
Ibrutinib-induced pyoderma gangrenosum.
710 started an oral ibrutinib therapy (3 × 140 mg/d), due to B-CLL. An ulcer biopsy revealed lymphocyte and neutrophil infiltration. No histopathologic signs of carcinoma or vasculitis were observed. After consultation with a hematologist, a tentative diagnosis of ibrutinib-induced pyoderma gangrenosum (PG) was established. In addition to ibrutinib discontinuation, daily prednisone dose was inc...
متن کاملPyoderma gangrenosum.
Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, noninfective chronic inflammatory skin disorder of unknown etiology. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, haematological diseases and malignancies. Characteristic lesions begin as pustule or vesiculopustule and progresses to an ulcer or deep erosion with violace...
متن کاملSunitinib induced pyoderma gangrenosum-like ulcerations
Pyoderma gangrenosum is a non-infectious neutro?philic skin disease commonly associated with underlying systemic diseases. Histopathological and laboratory diagnostics are unspecific in the majority of the cases and the diagnosis is made in accordance with the clinical picture. Here, we report the case of a 69-year old man with progredient pyoderma gangrenosum-like ulcerations under treatment w...
متن کاملComparison of Clinical Features between Pyoderma Gangrenosum Concomitant by Inflammatory Bowel Disease and Idiopathic Pyoderma Gangrenosum
BACKGROUND Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that is highly associated with inflammatory bowel disease (IBD). Certain PG patients with no systemic disorders have been diagnosed with idiopathic PG. This study sought to clarify the difference between PG with IBD and idiopathic PG based on clinical features, laboratory tests, and medications. METHODS Twelve patients wit...
متن کاملPyoderma gangrenosum – a review
Pyoderma gangrenosum (PG) is a rare noninfectious neutrophilic dermatosis. Clinically it starts with sterile pustules that rapidly progress and turn into painful ulcers of variable depth and size with undermined violaceous borders. The legs are most commonly affected but other parts of the skin and mucous membranes may also be involved. Course can be mild or malignant, chronic or relapsing with...
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ژورنال
عنوان ژورنال: BMJ Case Reports
سال: 2016
ISSN: 1757-790X
DOI: 10.1136/bcr-2015-213574